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TXNRD1 Antibody (Clone AT30F1)

Categories: [ Antibodies][ Monoclonal Antibodies]
TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01358
Size 100 µL
Host Type Mouse
Immunogen Recombinant human TXNRD1 (161-647aa) purified from E. coli
Specificity
Isotype IgG2b, k
Reacitivity Human
Clone Anti-human TXNRD1 mAb, clone AT30F1, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TXNRD1 protein.
Uniprot
Concentration 1 mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, Flow cytometry, ICC/IF
Other Names Thioredoxin reductase 1, GRIM-12, MGC9145, TR, TR1, TRXR1, TXNR, Thioredoxin reductase 1 Gene associated with retinoid IFN induced mortality 12 protein.
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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