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TNFa Antibody (Clone AT10A7)

Categories: [ Antibodies][ Monoclonal Antibodies]
TNF alpha, also known as Tumor necrosis factor alpha, is 157 amino acids (soluble form). This protein is produced by neutrophils, CD4+ T cells, macrophage, NK cells, LAK cells, astrocytes endothelial cells, and smooth muscle cells. TNF alpha is cytolytic and plays an important role in immune regulation including hemorrhagic tumor necrosis/cytotoxicity and inflammation, and in regulation of antiviral and immune proliferative and activation responses. Genetic variations in TNF are a cause of susceptibility psoriatic arthritis (PSORAS).
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01339
Size 100 µL
Host Type Mouse
Immunogen Recombinant human TNFa (57-233aa) purified from E. coli
Specificity
Isotype IgG2b,k
Reacitivity Human
Clone Anti-human TNFa mAb, clone AT10A7 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TNFa protein.
Uniprot
Concentration 1mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, Flow cytometry, ICC/IF
Other Names TNFA, TNFSF2, DIF (differentiation inducing factor ), CACHECTIN, DIF, TNF-alpha, Tumor necrosis factor alpha, Tumor necrosis factor alpha, TNF, tumor necrosis factor (TNF superfamily, member 2), TNF superfamily member 2,.
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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