STOM Antibody (Clone AT33F5)

STOM(stomatin) is a member of a highly conserved family of integral membrane proteins. This protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of STOM is associated with hereditary stomatocytosis, a form of hemolytic anemia. Although the wide distribution of stomatin and its constitutive expression suggest an important role for this protein in cell biology, perhaps as a house-keeping component, its function remains undetermined. The massive presence of stomatin in membrane-protruding folds and extensions suggests a possible structural role for this protein in the formation of these structures and/or the anchorage to the actin cytoskeleton.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01314
Size 100 µL
Host Type Mouse
Immunogen Recombinant human STOM (55-288aa) purified from E. coli
Specificity
Isotype IgG2b,k
Reacitivity Human
Clone Anti-human STOM mAb, clone AT33F5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human STOM protein.
Uniprot
Concentration 1mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, Flow cytometry, ICC/IF
Other Names Erythrocyte band 7 integral membrane protein isoform a, BND7, EPB7, EPB72.
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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