SNAI1 Antibody (Clone AT2D5)

Categories: [ Antibodies][ Monoclonal Antibodies]

SNAI1, also known as Snail homolog 1, is involved in the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. This protein binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. Both SNAI1 and SLUG belong to the snail C2H2-type zinc-finger protein family. SLUG is a transcriptional repressor, involved in the generation and migration of neural crest cells. SNAI1 is expressed in mesenchymal, epithelial cell lines and highest expression in kidney.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01597
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human SNAI1 (1-264aa) purified from E. coli
Specificity
Isotype	IgG2b,k
Reacitivity	Human
Clone	Anti-human SNAI1 mAb, clone AT2D5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SNAI1 protein.
Uniprot
Concentration	1mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB.
Other Names	Snail homolog 1, dJ710H13.1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1.
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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SNAI1 Antibody (Clone AT2D5)

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