SHMT1 Antibody (Clone AT26E5)

Categories: [ Antibodies][ Monoclonal Antibodies]

Serine hydroxymethyltransferase 1, also known as SHMT1, belongs to the SHMT family. This protein is cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5 10-methylene tetrahydrofolate. Also, SHMT1 preferentially supplies one-carbon units for thymidylate biosynthesis, depletes methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate and inhibits.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01582
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human SHMT1 (1-483aa) purified from E. coli
Specificity
Isotype	Mouse IgG1, k
Reacitivity	Human
Clone	Anti-human SHMT1 mAb, clone AT26E5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SHMT1 protein.
Uniprot
Concentration	1mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB, Flow cytometry, ICC/IF
Other Names	Serine hydroxymethyltransferase 1, CSHMT, SHMT
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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SHMT1 Antibody (Clone AT26E5)

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