QPRT Antibody (Clone AT24C4)

Categories: [ Antibodies][ Monoclonal Antibodies]

Quinolinate phosphoribosyltransferase, also known as QPRT, is a major enzyme in the catabolism of quinolinate. It is an intermediate in the tryptophannicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide and pyrophosphate. Elevation of QPRT levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01519
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human QPRT (1-297aa) purified from E. coli
Specificity
Isotype	Mouse IgG2a, k
Reacitivity	Human
Clone	Anti-human QPRT mAb, clone AT24C4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human QPRT protein.
Uniprot
Concentration	1mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB, Flow cytometry, ICC/IF
Other Names	Nicotinate nucleotide pyrophosphorylase (carboxylating), Nicotinate nucleotide pyrophosphorylase carboxylating, Quinolinate phosphoribosyltransferase, QPRTase, QAPRTase
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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QPRT Antibody (Clone AT24C4)

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