PPME1 Antibody (Clone AT29G3)

PPME1, also known protein phosphatase methylesterase-1(PME1), catalyzes the demethylation and inactivation of protein phosphatase (PP2A), which is a multimeric phosphoserine/ threonine protein phosphatase associated with growth inhibition and cell cycle arrest. It can demethylate PP2A catalytic subunit in vitro and okadaic acid treatment is capable of inhibiting this reaction. It is conserved from yeast to human and contains a motif found in lipases having a catalytic triad activated serine as their active site nucleophile.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01726
Size 100 µL
Host Type Mouse
Immunogen Recombinant human PPME1 (1-386aa) purified from E. coli
Specificity
Isotype IgG1, k
Reacitivity Human
Clone Anti-human PPME1 mAb, clone AT29G3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPME1 protein.
Uniprot
Concentration 1 mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB
Other Names Protein phosphatase methylesterase 1, FLJ22226, PME-1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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