PMVK Antibody (Clone AT21C10)

Categories: [ Antibodies][ Monoclonal Antibodies]

Phosphomevalonate kinase, also known as PMVK, is a cytosolic enzyme. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. Induced by sterol, PMVK participates in isopentenyl diphosphate biosynthesis via the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01702
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human PMVK (1-192aa) purified from E. coli
Specificity
Isotype	Mouse IgG2a heavy chain and kappa light chain.
Reacitivity	Human
Clone	Anti-human PMVK mAb, clone AT21C10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PMVK protein.
Uniprot
Concentration	1 mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol
Application	ELISA, WB, ICC/IF, and Flow cytometry.
Other Names	Phosphomevalonate kinase, HuMPMKI, PMK, PMKA, PMKASE, Phosphomevalonate kinase.
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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PMVK Antibody (Clone AT21C10)

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