PDZK1 Antibody (Clone AT1A2)

Categories: [ Antibodies][ Monoclonal Antibodies]

PDZK1 is PDZ domain-containing scaffolding protein with a 519 amino acid protein. PDZK1 mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. This protein is expressed in the kidney, pancreas, liver, gastrointestinal tract, and adrenal cortex. In situ hybridization experiments showed that the expression of PDZK1 was limited to epithelial cells. In addition, PDZK1 was overexpressed in selected tumors of epithelial origin.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01671
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human PDZK1 (1-519aa) purified from E. coli
Specificity
Isotype	IgG2b, k
Reacitivity	Human
Clone	Anti-human PDZK1 mAb, clone AT1A2, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PDZK1 protein.
Uniprot
Concentration	1 mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB, Flow cytometry, ICC/IF
Other Names	CAP70, CLAMP, NHERF-3, NHERF3, PDZD1.
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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PDZK1 Antibody (Clone AT1A2)

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