OTUB1 Antibody (Clone AT17E10)

Categories: [ Antibodies][ Monoclonal Antibodies]

Otubain 1, also known as OTUB1, is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system via its interaction with an ubiquitin protease and E3 ubiquitin ligase. This protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01625
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human OTUB1 (1-271aa) purified from E. coli
Specificity
Isotype	Mouse IgG1, k
Reacitivity	Human
Clone	Anti-human OTUB1 mAb, clone AT17E10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human OTUB1 protein.
Uniprot
Concentration	1 mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB, ICC/IF, Flow cyt
Other Names	Ubiquitin thioesterase Otubain 1, OTB1, OTu1, ubiquitin thioesterase Otubain 1 Deubiquitinating enzyme OTuB1, OTu domain containing ubiquitin aldehyde binding protein 1, Otubain 1.
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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OTUB1 Antibody (Clone AT17E10)

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