NUDT1 Antibody (Clone AT3B3)

Categories: [ Antibodies][ Monoclonal Antibodies]

NUDT1, also known as MTH1 is a 179 amino acid cytoplasmic protein that is a member of the nudix hydrolase family. Highly expressed in testis, thymus and proliferating blood lymphocytes, NUDT1 functions as an antimutagenic that hydrolyzes oxidized purine nucleoside triphosphates to their corresponding monophosphates. Through its ability to enzymatically hydrolyze ATP and GTP to AMP and GMP, respectively, NUDT1 prevents misincorporation of GTP into DNA, thus preventing A:T to C:G transversions.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01595
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human NUDT1 (1-156aa) purified from E. coli
Specificity
Isotype	Mouse IgG1, k
Reacitivity	Human
Clone	Anti-human NUDT1 mAb, clone AT3B3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NUDT1 protein.
Uniprot
Concentration	1 mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB, Flow cytometry, ICC/IF
Other Names	78-dihydro-8-oxoguanine triphosphatase, MTH1, 8-oxo-dGTPase, Nudix motif 1, 7,8-dihydro-8-oxoguanine triphosphatase
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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NUDT1 Antibody (Clone AT3B3)

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