NSE Antibody (Clone AT17D10)

Neuron-specific enolase (NSE) is a glycolytic isoenzyme which is located in central and peripheral neurons and neuroendocrine cells. This enzyme is released into the CSF when neural tissue is injured. Neoplasms derived from neural or neuroendocrine tissue may release NSE into the blood. NSE is a useful substance that has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, pancreatic endocrine tumors, and melanoma.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01594
Size 100 µL
Host Type Mouse
Immunogen Recombinant human NSE (1-434aa) purified from E. coli
Specificity
Isotype Mouse IgG2b heavy chain and kappa light chain
Reacitivity Human
Clone Anti-human NSE mAb, clone AT17D10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NSE protein.
Uniprot
Concentration 1 mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, Flow cytometry, ICC/IF
Other Names
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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