MEMO1 Antibody (Clone AT1E9)

MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01522
Size 100 µL
Host Type Mouse
Immunogen Recombinant human MEMO1 (1-297aa) purified from E. coli
Specificity
Isotype IgG1,k
Reacitivity Human
Clone AT1E9
Uniprot
Concentration 1mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB
Other Names Protein MEMO1, C2orf4, CGI-27, MEMO, NS5ATP7
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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