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LSM5 Antibody (Clone AT25F8)

Categories: [ Antibodies][ Monoclonal Antibodies]
LSM5, also known as YER146W, is a 91 amino acid protein belonging to the snRNP Sm family. Localized to the nucleus, LSm5 has been found to play a role in the formation and function of the U6 snRNP. Specifically, LSm5 binds to the 3' end of U6 snRNA and facilitates U4/U6 duplex formation. Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01485
Size 100 µL
Host Type Mouse
Immunogen Recombinant human LSM5 (1-91aa) purified from E. coli
Specificity
Isotype Mouse IgG2a, k
Reacitivity Human
Clone Anti-human LSM5 mAb, clone AT25F8, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human LSM5 protein.
Uniprot
Concentration 1 mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, Flow cytometry, ICC/IF
Other Names u6 snRNA-associated Sm-like protein LSm5 isoform a, LSM5 homolog, u6 small nuclear RNA associated (S.cerevisiae), YER146W
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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