ING2 Antibody (Clone AT39E5)

Categories: [ Antibodies][ Monoclonal Antibodies]

ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01441
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human ING2 (1-280aa) purified from E. coli
Specificity
Isotype	IgG1b,k
Reacitivity	Human
Clone	Anti-human ING2 mAb, clone AT39E5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ING2 protein.
Uniprot
Concentration	1mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB, ICC/IF
Other Names	inhibitor of growth protein 2, ING1L, P33ing2.
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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ING2 Antibody (Clone AT39E5)

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