IL-2 Antibody (Clone AT2D5)

IL-2 (Interleukin-2) is 153 amino acid protein. IL-2 produced by T cells in response to antigenic or mitogenic stimulation. This protein is required for T cell proliferation and other activities crucial to regulation of the immune response. IL-2 can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. Three different IL-2 dependent signal transduction pathways have been identified: the c-Fos/c-Jun induction pathway mediated by Src family protein-tyrosine kinases; the c-Myc induction pathway; and the Rapamycin-sensitive pathway.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01436
Size 100 µL
Host Type Mouse
Immunogen Recombinant human IL-2 (22-153aa) purified from E. coli
Specificity
Isotype IgG2b,k
Reacitivity Human
Clone Anti-human IL-2 mAb, clone AT2D5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IL-2 protein.
Uniprot
Concentration 1 mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, Flow cytometry.
Other Names IL-2, TCGF, Aldesleukin, T-cell growth factor, Interleukin-2, IL2, interleukin 2.
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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