HTATIP2 Antibody (Clone AT5D6)

Categories: [ Antibodies][ Monoclonal Antibodies]

HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy.

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Data Sheet	Click for Datasheet
Catalog Number	MA01426
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human HTATIP2 (1-242aa) purified from E. coli
Specificity
Isotype	IgG2a, k
Reacitivity	Human
Clone	Anti-human HTATIP2 mAb, clone AT5D6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human HTATIP2 protein.
Uniprot
Concentration	1 mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB, Flow cytometry, ICC/IF
Other Names	Oxidoreductase HTATP2, CC3, TIP30, SDR44u1, Oxidoreductase HTATP2, HTATIP 2, HTATIP-2, CC-3, TIP 30, TIP-30
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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HTATIP2 Antibody (Clone AT5D6)

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