HMGB1 Anti-Human Antibody (Clone J2E1)

High mobility group box1 protein (HMGB1) is a very abundant chromatin-binding protein residing in the eukaryotic cell nucleus and acting in the assembly of nucleoprotein complexes. Inside the cell, HMGB1 binds to DNA and has a role in transcriptional regulation. Outside the cell, HMGB1 acts as a cytokine and has activities that resemble those of tumor necrosis factor.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01416
Size 100 µL
Host Type Mouse
Immunogen Recombinant human HMGB1 (1-215aa) purified from High Five (Trichoplusia ni) insect cells.
Specificity
Isotype Mouse IgG2b heavy chain and kappa light chain
Reacitivity Human
Clone Anti-human HMGB1 mAb, clone J2E1, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice
Uniprot
Concentration 1 mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, IHC
Other Names
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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