CMBL Anti-Human Antibody (Clone AT2B11)

Categories: [ Antibodies][ Monoclonal Antibodies]

MBL(carboxymethylenebutenolidase homolog) is a 245 amino acid cytosolic protein and cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL is the human homolog of Pseudomonas dienelactone hydrolase, a protein that participates in the bacterial halocatechol degradation pathway. That is ubiquitously expressed with high expression in liver, colon, kidney and small intestine, where it acts as a bioactivating enzyme for a prodrug type angiotensin II type 1 receptor antagonist known as olmesartan medoxomil. CMBL is inhibited by p-chloromercuribenzoate (PCMB).

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01185
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human CMBL (1-245aa) purified from E. coli
Specificity
Isotype	Mouse IgG2a heavy chain and l (lambda) light chain
Reacitivity	Human
Clone	AT2B11
Uniprot
Concentration	1 mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB
Other Names
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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CMBL Anti-Human Antibody (Clone AT2B11)

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