Cathepsin D Anti-Human Antibody (Clone 4G2)

The aspartic protease cathepsin D is one of the major proteolytic enzymes in lysosomes. The cathepsin D gene locates on chromosome 11p15.5 and spans approximately 11 kb with nine exons. Initially synthesized as an inactive precursor of pro-cathepsin D, the enzyme is subsequently converted to its active forms by proteolytic processing. Breast cancer cells, unlike normal cells, secrete high levels of pro-cathepsin D
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01141
Size 100 µL
Host Type Mouse
Immunogen Recombinant human Cathepsin D (21-412 aa) purified from E. coli
Specificity
Isotype Mouse IgG2b heavy chain and kappa light chain
Reacitivity Human
Clone Anti-human cathepsin D mAb, clone 4G2, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice
Uniprot
Concentration 1mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB
Other Names
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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