C-ERC/Mesothelin (22A31) Anti-Human Mouse IgG MoAb

Erc has been identified as a gene showing stronger expression in cancer-affected renal cell than in normal renal tissue in Eker rats (a rat model of renal cancer). The human homologue of the protein encoded by this gene is called MPF (megakaryocyte potentiating factor) or mesothelin. This protein is detected especially prominently in mesothelial cells, and its involvement has been suggested in the development of mesothelioma, making it a promising tumor marker. In humans, involvement of this protein has also been suggested in the development of pancreatic, ovarian and pulmonary cancers, etc. The protein is expressed as a GPI anchor-type membranous protein (about 71 kDa in molecular weight), which is thought to be digested by a furin-like protease to yield fragments about 31 kDa and 40 kDa in size. We have prepared an antibody specific to C-ERC/Mesothelin (40 kDa fragment).
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01124
Size 100 μg
Host Type Mouse
Immunogen Recombinant protein for Human C-ERC/Mesothelin
Specificity
Isotype IgG
Reacitivity Human
Clone 22A31
Uniprot
Concentration 1.0 mL deionized water will be added to the product, then its concentration comes to 100 μg/mL.
Dilution
Formulation Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
Application IHC, WB, flow cytometry analysis.
Other Names
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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