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BMPR1B, 14-126aa, Human, His tag, E.coli

Categories: [Proteins / Peptides]
BMPR1B also known as bone morphogenetic protein receptor type-1B isoform b. BMPR1B is on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. It's receptor for BMP7/OP-1 and GDF5. Recombinant human BMPR1B was expressed in E.coli and purified by using conventional chromatography techniques
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Properties

Data Sheet Click for Datasheet
Catalog Number TP01355
Size 20 µg
Host E.coli
Accession
Molecular Weight 15.1kDa (136aa) confirmed by MALDI-TOF
AP_Mol_Weight
Tag N-6His
Sequences MGSSHHHHHHSSGLVPRGSHMGSKKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHR
Purity > 95% by HPLC
Concentration 0.5mg/ml (determined by Bradford assay)
Formulation Liquid. In Phosphate buffered saline (pH7.4) containing 20% glycerol, 1mM DTT, 0.1mM PMSF
Other Names Bone morphogenetic protein receptor type-1B isoform b, ALK-6, ALK6, CDw293
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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