Anti-Mouse CCL2 Monoclonal Antibody

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02251
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Mcp1
Specificity Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level).1 Publication
Isotype IgG1
Reacitivity Mouse
Clone 2220
Uniprot P13500
Concentration None
Dilution WB 1:500-1:5000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names C-C motif chemokine 2,CCL2,CCL2,Chemokine (C C motif) ligand 2,GDCF 2,GDCF-2,GDCF2,HC11,HSMCR30,JE,MCAF,MCP 1,MCP-1,MCP1,MGC9434,Monocyte chemoattractant protein 1,Monocyte chemotactic and activating factor,Monocyte chemotactic protein 1,Monocyte secretory protein JE,SCYA2,Small inducible cytokine A2 (monocyte chemotactic protein 1,homologous to mouse Sig je),Small inducible cytokine A2,Small inducible cytokine subfamily A (Cys Cys),member 2,Small-inducible cytokine A2,SMC CF,SMC-CF,SMCCF
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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