Anti-Human SDCCAG8 Monoclonal Antibody

SDCCAG8,also named as CCCAP and NY-CO-8,plays a role in the establishment of cell polarity and epithelial lumen formation. It may play a role in ciliogenesis. Loss of SDCCAG8 function as a cause of a retinal-renal ciliopathy and validates exome capture analysis for broadly heterogeneous single-gene disorders. SDCCAG8 is localized at both centrioles and interacts directly with OFD1 (oral-facial-digital syndrome 1),which is associated with NPHP-RC.