Anti-Human PSAP Monoclonal Antibody

ACPP is also named as PAP(prostatic acid phosphatase),5'-nucleotidase,thiamine monophosphatas and Belongs to the histidine acid phosphatase family.This enzyme is a homodimeric glycoprotein with a subunit molecular mass of 50 kDa and is an androgen-stimulated secretory product of the human prostate gland.It is also a non-specific phosphatase and has been implicated in the progression of prostate cancer,which inactivates LPA in human seminal plasma. This protein has three glycosylation sites.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01839
Size 100μl
Host Type Mouse
Immunogen Fusion protein of ACPP
Specificity Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Isoform 2 also expressed in the sarcolemma of skeletal muscle. Levels of this cellular isoform decreased in prostate cancer.
Isotype IgG2a
Reacitivity Human
Clone 220
Uniprot P15309
Concentration None
Dilution WB 1:200-1:1000, IHC 1:20-1:200
Formulation
Application WB,IHC,ELISA
Other Names 5'-NT,5'-nucleotidase,Acid phosphatase prostate,ACP 3,ACP3,acpP,Ecto-5'-nucleotidase,PAP,PPAP,Prostatic acid phosphatase,Prostatic acid phosphotase,Thiamine monophosphatase,TMPase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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