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Anti-Human/Pig BMP2 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02438
Size 100μl
Host Type Mouse
Immunogen Fusion Protein of BMP2
Specificity Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
Isotype IgG2a
Reacitivity Human,Pig
Clone 1C5C2
Uniprot P12643
Concentration None
Dilution WB 1:1000-1:10000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names BDA2,BMP-2,BMP-2A,Bmp2,BMP2,BMP2A,Bone morphogenetic protein 2,Bone morphogenetic protein 2A
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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