Anti-Human Phospho-BCL2 (Thr56) Polyclonal Antibody

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01514
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Bcl-2 around the phosphorylation site of Thr56
Specificity Expressed in a variety of tissues.
Isotype IgG
Reacitivity Human
Clone
Uniprot P10415
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, IP 1:200-1:500, ELISA 1:20000
Formulation
Application WB,IHC-p,IF,IP,ELISA
Other Names Apoptosis regulator Bcl 2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl2,AW986256,B cell CLL/lymphoma 2,B cell leukemia/lymphoma 2,Bcl-2,Bcl2,BCL2,C430015F12Rik,D630044D05Rik,D830018M01Rik,Leukemia/lymphoma,B-cell,2,Oncogene B-cell leukemia 2,PPP1R50,Protein phosphatase 1,regulatory subunit 50
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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