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Anti-Human PDGFRA Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Platelet-derived growth factor receptor alpha (PDGFRA,also known as CD140a) is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA is implicated in the regulation of embryonic development,tumorigenesis,cell proliferation,survival and chemotaxis. Mutations in PDGFRA gene have been associated with idiopathic hypereosinophilic syndrome,somatic and familial gastrointestinal stromal tumors,and a variety of other cancers.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02310
Size 100μl
Host Type Mouse
Immunogen Fusion protein of PDGFRA
Specificity Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue.
Isotype IgG1
Reacitivity Human
Clone 134
Uniprot P16234
Concentration None
Dilution WB 1:2000-1:20000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A,CD140a,CD140a antigen,MGC74795,PDGF alpha chain,PDGF-R-alpha,PDGFR 2,PDGFR alpha,PDGFR2,PDGFRA,PDGFRA/BCR fusion,PGFRA,Platelet derived growth factor receptor 2,Platelet derived growth factor receptor alpha,Platelet derived growth factor receptor alpha polypeptide,Platelet derived growth factor receptor,Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein,RHEPDGFRA
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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