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Anti-Human OLR1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12671
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human OLR1
Specificity Expressed at high level in endothelial cells and vascular-rich organs such as placenta, lung, liver and brain, aortic intima, bone marrow, spinal cord and substantia nigra. Also expressed at the surface of dendritic cells. Widely expressed at intermediate and low level.
Isotype IgG
Reacitivity Human
Clone
Uniprot P78380
Concentration 0.5 mg/mL
Dilution WB 1:200-1:1000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names C-type lectin domain family 8 member A,CLEC8A,hLOX 1,hLOX-1,Lectin like oxidized LDL receptor 1,Lectin like oxLDL receptor 1,Lectin type oxidized LDL receptor 1,Lectin-like oxidized LDL receptor 1,Lectin-like oxLDL receptor 1,Lectin-type oxidized LDL receptor 1,low density lipoprotein oxidized,receptor 1,LOX-1,LOXIN,Olr1,OLR1,Ox LDL receptor 1,Ox-LDL receptor 1,Oxidised low density lipoprotein (lectin like) receptor 1,Oxidized low density lipoprotein receptor 1,Oxidized low density lipoprotein receptor 1 soluble form,Oxidized low-density lipoprotein receptor 1,SCARE1,Scavenger receptor class E,member 1,SLOX1,soluble form,SR-EI
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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