Anti-Human/Mouse SYVN1 Polyclonal Antibody

This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12752
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human SYVN1
Specificity Ubiquitously expressed, with highest levels in liver and kidney (at protein level). Up-regulated in synovial tissues from patients with rheumatoid arthritis (at protein level).
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q86TM6
Concentration 0.1 mg/mL
Dilution WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names 1200010C09Rik,DER3,E3 ubiquitin-protein ligase synoviolin,HMG coA reductase degradation 1 homolog,HRD1,KIAA1810,MGC40372,OTTHUMP00000230429,OTTHUMP00000230430,OTTHUMP00000230431,OTTHUMP00000230432,Synovial apoptosis inhibitor 1,Synovial apoptosis inhibitor 1,synoviolin,Synoviolin 1,Synoviolin 1 isoform b,SYNOVIOLIN,SYVN1,SYVN1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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