Anti-Human/Mouse SUFU Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

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Data Sheet	Click for Datasheet
Catalog Number	PA12858
Size	100μl
Host Type	Rabbit
Immunogen	Recombinant protein of human SUFU
Specificity	Ubiquitous in adult tissues. Detected in osteoblasts of the perichondrium in the developing limb of 12-week old embryos. Isoform 1 is detected in fetal brain, lung, kidney and testis. Isoform 2 is detected in fetal testis, and at much lower levels in fetal brain, lung and kidney.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	Q9UMX1
Concentration	0.1 mg/mL
Dilution	WB 1:200-1:1000, IHC 1:15-1:50
Formulation
Application	WB,IHC,ELISA
Other Names	OTTHUMP00000020374,OTTHUMP00000020377,OTTHUMP00000020379,PRO1280,SU FU,SU(F)U,Su(fu),SUFU,SUFU negative regulator of hedgehog signaling,SUFU,SUFUH,SUFUXL,Suppressor of fused homolog (Drosophila),Suppressor of fused homolog
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse SUFU Polyclonal Antibody

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