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Anti-Human/Mouse SIGLEC5 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12423
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human SIGLEC5
Specificity Expressed by monocytic/myeloid lineage cells. Found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. Expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O15389
Concentration 0.3 mg/mL
Dilution WB 1:200-1:1000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names CD170,CD170 antigen,CD33 antigen-like 2,CD33L2,mSiglec-F,OB-binding protein 2,OB-BP2,OBBP2,Obesity-binding protein 2,Sialic acid binding Ig-like lectin 5,Sialic acid binding immunoglobulin-like lectin 5,Sialic acid-binding Ig-like lectin 5,Sialic acid-binding Ig-like lectin F,SIGL5,Siglec-5,Siglec-F variant,Siglec5,Siglecf
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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