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Anti-Human/Mouse/Rat SOCS3 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12697
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human SOCS3
Specificity Widely expressed with high expression in heart, placenta, skeletal muscle, peripheral blood leukocytes, fetal and adult lung, and fetal liver and kidney. Lower levels in thymus.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O14543
Concentration 0.4 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names ATOD4,CIS 3,CIS-3,CIS3,Cish3,Cytokine induced SH2 protein 3,Cytokine-inducible SH2 protein 3,E2a Pbx1 target gene in fibroblasts 10,EF 10,MGC71791,SOCS 3,SOCS-3,Socs3,SOCS3,SSI 3,SSI-3,SSI3,STAT induced STAT inhibitor 3,STAT-induced STAT inhibitor 3,Suppressor of cytokine signaling 3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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