Anti-Human/Mouse/Rat RB1 Polyclonal Antibody

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12524
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human RB1
Specificity Expressed in the retina.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P06400
Concentration 0.4 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names Exon 17 tumor GOS561 substitution mutation causes premature stop,GOS563 exon 17 substitution mutation causes premature stop,OSRC,Osteosarcoma,p105-Rb,P105RB,PP105,pp110,PPP1R130,pRb,Prepro retinoblastoma associated protein,Protein phosphatase 1 regulatory subunit 130,Rb,RB transcriptional corepressor 1,RB,RB1,RB1 gene,Retinoblastoma 1,Retinoblastoma suspectibility protein,Retinoblastoma-associated protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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