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Anti-Human/Mouse/Rat Phospho-RUNX1 (Ser249) Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01655
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human RUNX1 around the phosphorylation site of Ser249
Specificity Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q01196
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:5000
Formulation
Application WB,ELISA
Other Names Acute myeloid leukemia 1,Acute myeloid leukemia 1 protein,alpha subunit core binding factor,AML 1,AML1,AML1 EVI 1,AML1 EVI 1 fusion protein,Aml1 oncogene,AMLCR 1,AMLCR1,CBF alpha 2,CBF-alpha-2,CBFA 2,CBFA2,Core binding factor alpha 2 subunit,Core binding factor runt domain alpha subunit 2,Core-binding factor subunit alpha-2,EVI 1,EVI1,HGNC,Oncogene AML 1,Oncogene AML-1,OTTHUMP00000108696,OTTHUMP00000108697,OTTHUMP00000108699,OTTHUMP00000108700,OTTHUMP00000108702,PEA2 alpha B,PEA2-alpha B,PEBP2 alpha B,PEBP2-alpha B,PEBP2A2,PEBP2aB,Polyomavirus enhancer binding protein 2 alpha B subunit,Polyomavirus enhancer-binding protein 2 alpha B subunit,Run1,Runt related transcription factor 1,Runt-related transcription factor 1,RUNX 1,Runx1,RUNX1,SL3 3 enhancer factor 1 alpha B subunit,SL3-3 enhancer factor 1 alpha B subunit,SL3/AKV core binding factor alpha B subunit,SL3/AKV core-binding factor alpha B subunit
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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