Anti-Human/Mouse/Rat Phospho-p27 (Thr187) Polyclonal Antibody

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01649
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human p27 around the phosphorylation site of Thr187
Specificity Expressed in all tissues tested. Highest levels in skeletal muscle, lowest in liver and kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P46527
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names AA408329,AI843786,Cdki1b,CDKN 1B,CDKN 4,CDKN1B,CDKN4,CDN1B,Cyclin Dependent Kinase Inhibitor 1B,Cyclin dependent kinase inhibitor p27,Cyclin-dependent kinase inhibitor 1B (p27,Kip1),Cyclin-dependent kinase inhibitor 1B,Cyclin-dependent kinase inhibitor p27,Cyclin-dependent kinase inhibitor p27 Kip1,KIP 1,KIP1,MEN1B,MEN4,OTTHUMP00000195098,OTTHUMP00000195099,p27,p27 Kip1,P27-like cyclin-dependent kinase inhibitor,p27Kip1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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