Anti-Human/Mouse/Rat Phospho-IRS1 (Ser639) Polyclonal Antibody

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01581
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human IRS-1 around the phosphorylation site of S639.
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P35568
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names HIRS 1,HIRS1,Insulin receptor substrate 1,IRS 1,IRS-1,IRS1,IRS1,OTTHUMP00000164234
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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