Anti-Human/Mouse/Rat Phospho-CCR5 (Ser336) Polyclonal Antibody

Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01652
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human CKR-5 around the phosphorylation site of Ser336
Specificity Highly expressed in spleen, thymus, in the myeloid cell line THP-1, in the promyeloblastic cell line KG-1A and on CD4+ and CD8+ T-cells. Medium levels in peripheral blood leukocytes and in small intestine. Low levels in ovary and lung.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P51681
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names AM4 7,C C chemokine receptor type 5,C C CKR 5,C-C chemokine receptor type 5,C-C CKR-5,C-C motif chemokine receptor 5 A159A,CC Chemokine Receptor 5,CC Chemokine Receptor Type 5,CC CKR 5,CC-CKR-5,CCCKR 5,CCCKR5,CCR 5,CCR-5,CCR5,CCR5 chemokine (C C motif) receptor 5,CCR5,CD 195,CD195,CD195 Antigen,Chemokine C C motif receptor 5,Chemokine receptor CCR5,CHEMR13,CKR 5,CKR5,CMKBR 5,CMKBR5,FLJ78003,HIV 1 Fusion Coreceptor,HIV-1 fusion coreceptor,HIV1 fusion coreceptor,IDDM22,MIP-1 alpha receptor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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