Anti-Human/Mouse/Rat Phospho-CAV1 (Tyr14) Polyclonal Antibody

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01518
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Caveolin-1 around the phosphorylation site of Tyr14
Specificity Expressed in muscle and lung, less so in liver, brain and kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q03135
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names BSCL3,CAV,CAV1,CAV1,caveolae protein,22 kD,caveolin 1 alpha isoform,caveolin 1 beta isoform,Caveolin 1 caveolae protein 22kDa,Caveolin-1,Caveolin1,cell growth-inhibiting protein 32,CGL3,LCCNS,MSTP085,OTTHUMP00000025031,PPH3,VIP 21,VIP21
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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