Anti-Human/Mouse/Rat PGRMC1 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]

Progesterone receptor membrane component 1 (PGRMC1) is a member of a multi-protein progesterone-binding complex. However,PGRMC1 shares homology with cytochrome b5-related proteins rather than hormone receptors . It is a heme binding protein with biding sites for Src homology (SH2) and SH3 domain-containing proteins . PGRMC1 is overexpressed in a variety of cancers,and thus represents an important biomarker for cancer progression and a potential target for anticancer drugs . In nonmalignant tissues,PGRMC1 is highly expressed in the liver and kidney .

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA02533
Size	100μl
Host Type	Mouse
Immunogen	Fusion Protein of PGRMC1
Specificity	Widely expressed, with highest expression in liver and kidney.
Isotype	IgG1
Reacitivity	Human,Mouse,Rat
Clone	1C10D11
Uniprot	O00264
Concentration	None
Dilution	WB 1:1000-1:10000, IHC 1:50-1:500
Formulation
Application	WB,IHC,ELISA
Other Names	HPR6.6,Membrane associated progesterone receptor component 1,Membrane-associated progesterone receptor component 1,mPR,PGRC1,PGRMC,Pgrmc1,Progesterone binding protein,Progesterone receptor membrane component 1
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

Catalog NO.:	MA02533	Quantity:
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Anti-Human/Mouse/Rat PGRMC1 Monoclonal Antibody

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