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Anti-Human/Mouse/Rat MYOC Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Myocilin (MYOC),also known as TIGR or GLC1A,is a secreted glycoprotein of the olfactomedin family,originally identified in trabecular meshwork cells after prolonged treatment with glucocorticoids,and,independently,in the retina . It may participate in the obstruction of fluid outflow in the trabecular meshwork. Defects in MYOC are the cause of primary open angle glaucoma (POAG) .
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02511
Size 100μl
Host Type Mouse
Immunogen Fusion Protein of MYOC
Specificity Expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart and other tissues. Expressed predominantly in the retina. In normal eyes, found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, it is found in more regions of the meshwork and appeared more intensively than in normal eyes, regardless of the type or clinical severity of glaucoma.
Isotype IgG2a
Reacitivity Human,Mouse,Rat
Clone 4B1F6
Uniprot Q99972
Concentration None
Dilution WB 1:1000-1:10000
Formulation
Application WB,ELISA
Other Names GLC1A,GPOA,JOAG,JOAG1,Mutated trabecular meshwork-induced glucocorticoid response protein,MYOC,MYOC,Myocilin,Myocilin,trabecular meshwork inducible glucocorticoid,TIGR,Trabecular meshwork induced glucocorticoid response protein,Trabecular meshwork-induced glucocorticoid response protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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