Anti-Human/Mouse/Rat MLH1 Polyclonal Antibody

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12470
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human MLH1
Specificity Colon, lymphocytes, breast, lung, spleen, testis, prostate, thyroid, gall bladder and heart.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P40692
Concentration 0.8 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names COCA 2,COCA2,DNA mismatch repair protein Mlh1,FCC 2,FCC2,hMLH 1,hMLH1,HNPCC 2,HNPCC,HNPCC2,MGC5172,MLH 1,MLH1,MLH1,MutL homolog 1 (E. coli),MutL homolog 1,MutL homolog 1 colon cancer nonpolyposis type 2,MutL homolog 1,colon cancer,nonpolyposis type 2 (E. coli),MutL protein homolog 1,MutL,E. coli,homolog of,1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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