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Anti-Human/Mouse/Rat MAGEA3 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02246
Size 100μl
Host Type Mouse
Immunogen Fusion protein of MAGEA3
Specificity Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. Never expressed in kidney tumors, Leukemias and lymphomas.
Isotype IgG1
Reacitivity Human,Mouse,Rat
Clone 144
Uniprot P43357
Concentration None
Dilution WB 1:1000-1:10000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names Antigen MZ2 D,Antigen MZ2-D,Cancer/testis antigen 1.3,Cancer/testis antigen family 1 member 3,CT1.3,HIP8,HYPD,MAGA3,MAGE 3 antigen,MAGE family member A3,MAGE-3 antigen,MAGE3,MAGEA3,MAGEA6,Melanoma antigen family A 3,Melanoma associated antigen 3,Melanoma-associated antigen 3,MGC1461
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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