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Anti-Human/Mouse/Rat IFT88 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Intraflagellar transport (IFT),mediated by molecular motors and IFT particles,is an important transport process that occurs in the cilium and has been shown to be essential for the assembly and maintenance of cilia and flagella in many organisms. IFT88 (intraflagellar transport protein 88; also known as TG737 or TTC10) is a component of IFT particles and required for cilium biogenesis. Defects in IFT88/Tg737 lead to polycystic kidney disease (11062270). IFT88 localizes to spindle poles during mitosis and is required for spindle orientation in mitosis (21441926). This antibody was raised against the C-terminal region of human IFT88 and can detect the endogenous level of IFT88.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02234
Size 100μl
Host Type Mouse
Immunogen Fusion protein of IFT88
Specificity Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.
Isotype IgG1
Reacitivity Human,Mouse,Rat
Clone 346
Uniprot Q13099
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200
Formulation
Application WB,IHC,IF,ELISA
Other Names D13S1056E,DAF19,hTg737,Ift88,IFT88,Intraflagellar transport 88 homolog,Intraflagellar transport protein 88 homolog,MGC26259,Polaris homolog,Probe hTg737 (polycystic kidney disease,autosomal recessive),Recessive polycystic kidney disease protein Tg737 homolog,RP11-172H24.2,Tetratricopeptide repeat domain 10,Tetratricopeptide repeat protein 10,TG737,TPR repeat protein 10,TTC10
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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