Anti-Human/Mouse/Rat HSP105 Polyclonal Antibody

Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12317
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human HSPH1
Specificity Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q92598
Concentration 0.2 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names Antigen NY CO 25,Antigen NY-CO-25,DKFZp686M05240,Heat shock 105kD alpha,Heat shock 105kD,Heat shock 105kD beta,Heat shock 105kDa protein 1,Heat shock 105kDa protein,Heat shock 105kDa/110kDa protein 1,Heat shock 110 kDa protein,Heat shock 110kDa protein,Heat shock protein 105 kDa,HS105,HSP105,HSP105A,HSP105B,HSP110,HSPH 1,Hsph1,KIAA0201,NY CO 25
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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