Anti-Human/Mouse/Rat HSD17B12 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation. Catalyzes the transformation of estrone (E1) into estradiol (E2), suggesting a central role in estrogen formation. Its strong expression in ovary and mammary gland suggest that it may constitute the major enzyme responsible for the conversion of E1 to E2 in women.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA12025
Size	100μl
Host Type	Rabbit
Immunogen	Recombinant protein of human HSD17B12
Specificity	Expressed in most tissues tested. Highly expressed in the ovary and mammary. Expressed in platelets.
Isotype	IgG
Reacitivity	Human,Mouse,Rat
Clone
Uniprot	Q53GQ0
Concentration	0.3 mg/mL
Dilution	WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application	WB,IHC,ELISA
Other Names	12,3-ketoacyl-CoA reductase,short chain,17 beta HSD 12,17 beta hydroxysteroid dehydrogenase 12,17-@beta-HSD XII,17-@beta-hydroxysteroid dehydrogenase XII,17-beta-HSD 12,17-beta-hydroxysteroid dehydrogenase 12,17beta HSD type 12,3 ketoacyl CoA reductase,3-ketoacyl-CoA reductase,DHB12,Estradiol 17 beta dehydrogenase 12,Estradiol 17-beta-dehydrogenase 12,HSD17B12,Hydroxysteroid (17-beta) dehydrogenase 12,KAR,KIK-I,Kik1,SDR12C1,Short chain dehydrogenase/reductase family 12C member 1,Steroid dehydrogenase homolog
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse/Rat HSD17B12 Polyclonal Antibody

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