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Anti-Human/Mouse/Rat DNMT3A Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12837
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human DNMT3A
Specificity Highly expressed in fetal tissues, skeletal muscle, heart, peripheral blood mononuclear cells, kidney, and at lower levels in placenta, brain, liver, colon, spleen, small intestine and lung.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9Y6K1
Concentration 0.4 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names DNA (cytosine 5) methyltransferase 3 alpha,DNA (cytosine 5) methyltransferase 3A,DNA (cytosine-5)-methyltransferase 3A,DNA cytosine methyltransferase 3A2,DNA methyltransferase 3 alpha,DNA methyltransferase 3a,DNA methyltransferase HsaIIIA,DNA MTase HsaIIIA,DNM3A,DNMT 3a,DNMT,Dnmt3a,DNMT3A2,M.HsaIIIA,MCMT,OTTHUMP00000201149,TBRS
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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