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Anti-Human/Mouse/Rat CHEK1 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
CHEK1(Checkpoint kinase-1) is also named as CHK1 and belongs to the protein kinase superfamily. It is implicated in a circuit in which it activates checkpoints,DNA repair and proliferating cell nuclear antigen and FANCD2 monoubiquitinylation. CHEK1 protects vertebrate cells against spontaneous chromosome missegregation and is required to sustain anaphase delay when spindle function is disrupted by taxol. It has 3 isoforms produced by alternative splicing with the molecular mass of 54 kDa,44 kDa and 50 kDa.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01916
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Chk1
Specificity Expressed ubiquitously with the most abundant expression in thymus, testis, small intestine and colon.
Isotype IgG2b
Reacitivity Human,Mouse,Rat
Clone 32
Uniprot O14757
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200
Formulation
Application WB,IHC,ELISA
Other Names C85740,Cell cycle checkpoint kinase,Checkpoint,S. pombe,homolog of,1,Checkpoint kinase 1,Checkpoint kinase 1 homolog (S. pombe),CHEK 1,Chek1,Chk 1,Chk1,CHK1 checkpoint homolog (S. pombe),CHK1,EC 2.7.11.1,rad27,Serine/threonine protein kinase Chk1,Serine/threonine-protein kinase CHK1,STT3,subunit of the oligosaccharyltransferase complex,homolog A (S. cerevisiae)
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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