Anti-Human/Mouse/Rat CFL1 Monoclonal Antibody

Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor)/cofilin family that is a key regulator of actin dynamics and essential for cellular motility,cytokinesis,and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation. Phosphorylation at Ser3 can inhibit its activity,also causing translocation from the nucleus to the cytoplasm.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01927
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Cofilin
Specificity Widely distributed in various tissues.
Isotype IgG2a
Reacitivity Human,Mouse,Rat
Clone 526
Uniprot P23528
Concentration None
Dilution WB 1:1000-1:10000, IHC 1:20-1:200, IF 1:20-1:200
Formulation
Application WB,IHC,IF,ELISA
Other Names 18 kDa phosphoprotein,CFL 1,CFL,CFL1,COF1,Cofilin 1,Cofilin 1 non muscle,Cofilin,Cofilin non muscle isoform,Cofilin-1,epididymis secretory protein Li 15,HEL-S-15,non-muscle isoform,p18
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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