Anti-Human/Mouse/Rat CD284 Monoclonal Antibody

TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02574
Size 100μl
Host Type Mouse
Immunogen Fusion Protein of CD284
Specificity Highly expressed in placenta, spleen and peripheral blood leukocytes. Detected in monocytes, macrophages, dendritic cells and several types of T-cells.
Isotype IgG2b
Reacitivity Human,Mouse,Rat
Clone 3G9A4
Uniprot O00206
Concentration None
Dilution WB 1:1000-1:10000, IHC 1:50-1:500
Formulation
Application WB,IHC,ELISA
Other Names ARMD10,CD284,CD284 antigen,Homolog of Drosophila toll,hToll,TLR 4,TLR4,TLR4,TOLL,Toll like receptor 4,Toll-like receptor 4
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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